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NSC 850745

SKU: orb3173167

Description

NSC 850745 is a selective and potent inhibitor of c-Met/STAT3, with IC50 values of 210 nM and 670 nM, respectively. It inhibits cell proliferation, induces G2/M phase arrest, and triggers apoptosis (cell death). NSC 850745 downregulates the expression of AKT-1, VEGF, and Bcl-2, while modulating p53, Bax, and caspase levels. This compound is utilized in cancer research, including studies on leukemia and colon cancer.

Research Area

Cardiovascular Research, Cell Biology, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetCaspase,STAT,Akt,VEGFR,MDM-2/p53,Bcl-2 Family,c-Met/HGFR,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Protocol Information