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NSC 850745

SKU: orb3173167

Description

NSC 850745 is a selective and potent inhibitor of c-Met/STAT3, with IC50 values of 210 nM and 670 nM, respectively. It inhibits cell proliferation, induces G2/M phase arrest, and triggers apoptosis (cell death). NSC 850745 downregulates the expression of AKT-1, VEGF, and Bcl-2, while modulating p53, Bax, and caspase levels. This compound is utilized in cancer research, including studies on leukemia and colon cancer.

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Key Properties

TargetSTAT,Akt,Bcl-2 Family,c-Met/HGFR,VEGFR,MDM-2/p53,Apoptosis,Caspase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

NSC 850745 (orb3173167)

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