NSC 66811

SKU: orb1306291

Description

NSC 66811

Research Area

Cell Biology

Key Properties

• CAS Number: 6964-62-1
• MW: 340.42
• Purity: 96.94%
• Formula: C₂₃H₂₀N₂O
• SMILES: Cc1ccc2ccc(C(Nc3ccccc3)c3ccccc3)c(O)c2n1
• Target: MDM-2/p53,Mdm2
• Solubility: 10% DMSO+90% Corn Oil:3.3 mg/mL (9.69 mM);DMSO:99 mg/mL (290.82 mM)

Bioactivity

• Target IC50:
  p53-MDM2:120 nM (ki)
• In Vitro:
  Due to the functional activation of p53, NSC 66811 (0, 5, 10, 20 μM) dose-dependently induce the accumulation of p53, MDM2, and p21cip1/waf.

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

p53-MDM2, p53, NSC 66811, NSC66811, NSC-66811, inhibit, Inhibitor, HCT-116, MDM2, MDM-2/p53

Compound Identifiers

PubChem CID

248986