NRX-1933

SKU: orb1301210

Description

NRX-1933 is a molecular glue degrader that stabilizes the interaction between oncogenic β-Catenin and the SCFβ-TrCP E3 ligase, promoting β-Catenin's ubiquitination and degradation. This tool compound is used in vitro and in vivo to study Wnt/β-catenin signaling in cancer and regenerative biology research.

Research Area

Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2763260-30-4
• MW: 350.26
• Purity: 99.79% (May vary between batches)
• Formula: C₁₄H₉F₃N₆O₂
• SMILES: FC(F)(F)c1ccc(C(=O)Nc2cccc(c2)-c2nn[nH]n2)c(=O)[nH]1
• Target: Others
• Solubility: 10% DMSO+90% Corn Oil:3.3 mg/mL (9.42 mM);DMSO:80 mg/mL (228.4 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, NRX 1933, NRX1933, NRX-1933, inhibit

Compound Identifiers

PubChem CID

137628322