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Nrf2 activator 18
Catalog Number: orb2814482
| Catalog Number | orb2814482 |
|---|---|
| Category | Small Molecules |
| Description | Nrf2 activator 18 (Compound 11a) is an orally active activator of the Keap1/Nrf2/HO-1 signaling pathway, promoting Nrf2 nuclear translocation and enhancing antioxidant effects. It inhibits IL-6 release with an IC50 of 4.816 μM. In a mouse model of PM2.5-induced lung injury, Nrf2 activator 18 demonstrates anti-inflammatory activity. |
| MW | 377.45 |
| Formula | C23H24FN3O |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
