NPX800

SKU: orb1297870

Description

NPX800 is a small molecule HSF1 inhibitor used in cancer research. It has been employed in both in vitro and in vivo studies to investigate the role of heat shock response in tumorigenesis and potential therapeutic strategies.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 1693734-80-3
• MW: 569.63
• Purity: 99.45% (May vary between batches)
• Formula: C₃₂H₃₂FN₅O₄
• SMILES: CCN1CCN(Cc2ccc3cc(ccc3n2)C(=O)Nc2cc(NC(=O)c3ccc4OCCOc4c3)ccc2F)CC1
• Target: HSP
• Solubility: DMSO:95 mg/mL (166.77 mM)

Bioactivity

• In Vitro:
  NPX800 inhibits cell viability of U20S with IC50 of 56 nM.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NXP800, NXP-800, NXP 800, inhibit, NPX 800, NPX800, NPX-800, HSP, Heat shock proteins, Inhibitor, HSF1, CCT 361814, CCT361814, CCT-361814

Compound Identifiers

PubChem CID

117996795