NPC-15437

SKU: orb1692846

Description

NPC-15437 dihydrochloride is a selective, cell-permeable PKC inhibitor (IC50 ~19-23 µM) that does not affect cAMP-dependent or Ca²⁺/calmodulin-dependent kinases. It serves as a key pharmacological tool for studying PKC signaling in vitro and has been used in research models investigating neuronal function and cardiovascular responses.

Research Area

Epigenetics & Chromatin, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 141774-20-1
• MW: 511.61
• Purity: >98%
• Formula: C₂₅H₅₀N₄O₂ ∙ 2HCl
• SMILES: NCCCC[C@H](N)C(NCC1N(CCCC1)C(CCCCCCCCCCCC)=O)=O.Cl.Cl
• Target: Kinase
• Solubility: Soluble in Water (up to 10 mg/ml).

Bioactivity

• Target IC50:
  PKC:19 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NPC15437, NPC-15437, NPC15437 (hydrochloride), NPC15437 dihydrochloride, NPC 15437, NPC 15437 (hydrochloride)

Compound Identifiers

PubChem CID

16219723