NPBA

• Catalog Number: orb2283547
• Category: Small Molecules
• Description: NPBA, a potassium K2P channel TASK-3 (KCNK9) agonist, concurrently functions as a blocker of the tandem pore domain weak inward rectifying K+ channel (TWIK2). This compound effectively inhibits NLRP3 inflammasome activation in macrophages [1].
• Purity: 98.00%
• MW: 353.3
• Biological Activity: NPBA, a potassium K2P channel TASK-3 (KCNK9) agonist, concurrently functions as a blocker of the tandem pore domain weak inward rectifying K+ channel (TWIK2). This compound effectively inhibits NLRP3 inflammasome activation in macrophages [1].
• CAS Number: 524033-40-7
• Formula: C₁₆H₁₄F₃N₃O₃
• SMILES: N(CCNC(=O)C1=CC=CC=C1)C2=C(C(F)(F)F)C=C(N(=O)=O)C=C2
• Storage: -20°C
• Note: For research use only