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NPA101.3

SKU: orb1739350

Description

NPA101.3 is a second-generation small molecule inhibitor targeting both RET and VEGFR2 kinases. It is a promising preclinical candidate for the treatment of RET-driven cancers, such as thyroid and non-small cell lung cancer, with demonstrated activity in relevant in vitro and in vivo models.

Images & Validation

Key Properties

CAS Number1839155-15-5
MW528.62
FormulaC29H28N4O4S
SMILESC(C(NC=1C=C(C(C)(C)C)ON1)=O)C2=CC=C(N3C=4C(=CC(=CC4)C5=CC=C(S(C)(=O)=O)C=C5)N=C3)C=C2
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information