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NP3-146

SKU: orb1691227

Description

NP3-146 (NLRP3-IN-5) is a selective NLRP3 inflammasome inhibitor used in autoimmune disease research. It has demonstrated inhibitory activity in both cellular assays and animal models of inflammation, supporting its utility for in vitro and in vivo mechanistic studies.

Research Area

Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

CAS Number210826-47-4
MW442.96
Purity99.21%
FormulaC20H27ClN2O5S
SMILESO=C(NC=1C(=CC(Cl)=CC1C(C)C)C(C)C)NS(=O)(=O)C=2OC=C(C2)C(O)(C)C
TargetNOD,NOD-like Receptor (NLR)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NLRP3, NLRP3 IN 5, NLRP3IN5, NLRP-3-IN-5, NLRP3-IN-5

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Key Properties

No computed properties available.

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Protocol Information

NP3-146 (orb1691227)

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Available Sizes

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1 mg
$ 440.00
5 mg
$ 1,010.00
10 mg
$ 1,330.00
25 mg
$ 1,990.00
50 mg
$ 2,660.00
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