NP3-146

SKU: orb1691227

Description

NP3-146 (NLRP3-IN-5) is a selective NLRP3 inflammasome inhibitor used in autoimmune disease research. It has demonstrated inhibitory activity in both cellular assays and animal models of inflammation, supporting its utility for in vitro and in vivo mechanistic studies.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 210826-47-4
• MW: 442.96
• Purity: 99.21% (May vary between batches)
• Formula: C₂₀H₂₇ClN₂O₅S
• SMILES: O=C(NC=1C(=CC(Cl)=CC1C(C)C)C(C)C)NS(=O)(=O)C=2OC=C(C2)C(O)(C)C
• Target: NOD-like Receptor (NLR),NOD

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NLRP3, NLRP3 IN 5, NLRP3IN5, NLRP-3-IN-5, NLRP3-IN-5

Compound Identifiers

PubChem CID

10195003