NoxA1ds acetate(1435893-78-9 free base)

SKU: orb1296466

Description

NoxA1ds acetate is a highly potent and selective NOX1 inhibitor (IC50: 20 nM) that suppresses superoxide production in HT-29 colon cancer cells and attenuates hypoxia-induced endothelial cell migration. This makes it a valuable research tool for studying NOX1's role in cancer biology, angiogenesis, and related oxidative stress pathways in vitro.

Research Area

Immunology & Inflammation

Key Properties

• Target: NADPH-oxidase
• MW: 1185.35
• Purity: 96.92% (May vary between batches)
• Formula: C₅₂H₉₂N₁₄O₁₇
• SMILES: C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)O)N.CC(=O)O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NADPHoxidase, NoxA1ds acetate(1435893 78 9 free base), NoxA1ds acetate(1435893789 free base), NoxA-1ds acetate(1435893-78-9 free base), NoxA1ds acetate(1435893-78-9 free base), NOX1

Compound Identifiers

PubChem CID

170915643