Notum-IN-1

SKU: orb1744355

Description

Notum-IN-1 is an orally bioavailable, brain-penetrant small molecule that selectively inhibits the enzyme Notum, a key negative regulator of Wnt signaling. Its application in research includes both in vitro mechanistic studies and in vivo models for investigating Wnt/β-catenin pathway restoration in neurological and bone-related disorders.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 338419-11-7
• MW: 244.08
• Formula: C₉H₇Cl₂N₃O
• SMILES: OCC1=CN(N=N1)C1=CC(Cl)=C(Cl)C=C1
• Target: Wnt/beta-catenin,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

1475797