NOS1-IN-1

SKU: orb1692664

Description

NOS1-IN-1 is a potent, selective, and cell-permeable inhibitor of neuronal nitric oxide synthase (nNOS), exhibiting significant selectivity over eNOS and iNOS. Its utility extends to in vitro and in vivo research models for investigating neurological disorders, including cerebral palsy and stroke pathology.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 357965-99-2
• MW: 589.37
• Purity: 99.70%
• Formula: C₁₄H₂₄F₉N₇O₈
• SMILES: OC(C(F)(F)F)=O.NCCNC[C@@H](N)CCCNC(N[N+]([O-])=O)=N.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
• Target: NO Synthase,NOS
• Solubility: H2O:5 mg/mL (8.48 mM);DMSO:45 mg/mL (76.35 mM)

Bioactivity

• Target IC50:
  nNOS:120 nM (Ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

nNOS Inhibitor I, NOS, NOS1-IN-1

Compound Identifiers

PubChem CID

71311606