Nortriptyline hydrochloride

SKU: orb1308969

Description

Nortriptyline hydrochloride is the active N-demethylated metabolite of amitriptyline, functioning as a tricyclic antidepressant. It is utilized in research models of major depressive disorder and dysthymia to investigate its mechanisms in neurotransmitter reuptake inhibition, employing both in vitro binding assays and in vivo behavioral studies.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 894-71-3
• MW: 299.84
• Purity: >99.99% (May vary between batches)
• Formula: C₁₉H₂₂ClN
• SMILES: Cl.CNCC\C=C1\c2ccccc2CCc2ccccc12
• Target: Autophagy,Norepinephrine,Drug Metabolite,Adrenergic Receptor,Histamine Receptor,5-HT Receptor,Apoptosis,Dopamine Receptor,AChR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.67 mM);Ethanol:54 mg/mL (180.1 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

depression, Desitriptilina, Desitriptyline HCl, Desmethylamitriptyline, Desmethylamitriptyline Hydrochloride, Desmethylamitriptyline hydrochloride, Dopamine, Dopamine Receptor, Drug Metabolite, DopamineReceptor, DrugMetabolite, 5-HT, 5HT Receptor, 5HTReceptor, Adrenergic Receptor, AdrenergicReceptor, Autophagy, Apoptosis, Inhibitor, Histamine Receptor, HistamineReceptor, H1 receptor, ELF 101 Hydrochloride, ELF101 Hydrochloride, ELF-101 hydrochloride, ELF-101 Hydrochloride, EN-7048 Hydrochloride, EN-7048 hydrochloride, EN7048 Hydrochloride, EN 7048 Hydrochloride, metabolite, mAChR, inhibit, Noradrenaline transporter (Sodium-dependent), Nortriptyline, Nortriptyline Hydrochloride, Nortriptyline hydrochloride, Sert (Sodium-dependent), tumor, tricyclic antidepressant

Compound Identifiers

PubChem CID

441358