Nortriptyline HCl

SKU: orb1308969

Description

Nortriptyline hydrochloride is the active N-demethylated metabolite of amitriptyline, functioning as a tricyclic antidepressant. It is utilized in research models of major depressive disorder and dysthymia to investigate its mechanisms in neurotransmitter reuptake inhibition, employing both in vitro binding assays and in vivo behavioral studies.

Research Area

Neuroscience

Key Properties

• CAS Number: 894-71-3
• MW: 299.84
• Purity: >98%
• Formula: C₁₉H₂₂ClN
• SMILES: Cl.CNCC\C=C1\c2ccccc2CCc2ccccc12
• Target: Monoamine transporter
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.67 mM);Ethanol:54 mg/mL (180.1 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

depression, Desitriptilina, Desitriptyline HCl, Desmethylamitriptyline, Desmethylamitriptyline Hydrochloride, Desmethylamitriptyline hydrochloride, Dopamine, Dopamine Receptor, Drug Metabolite, DopamineReceptor, DrugMetabolite, 5-HT, 5HT Receptor, 5HTReceptor, Adrenergic Receptor, AdrenergicReceptor, Autophagy, Apoptosis, Inhibitor, Histamine Receptor, HistamineReceptor, H1 receptor, ELF 101 Hydrochloride, ELF101 Hydrochloride, ELF-101 hydrochloride, ELF-101 Hydrochloride, EN-7048 Hydrochloride, EN-7048 hydrochloride, EN7048 Hydrochloride, EN 7048 Hydrochloride, metabolite, mAChR, inhibit, Noradrenaline transporter (Sodium-dependent), Nortriptyline, Nortriptyline Hydrochloride, Nortriptyline hydrochloride, Sert (Sodium-dependent), tumor, tricyclic antidepressant

Compound Identifiers

PubChem CID

441358