Norharmane

SKU: orb1303289

Description

Norharmane, a naturally occurring β-carboline originally identified in Zygophyllaceae plants, is used in research as a monoamine oxidase inhibitor and a fluorescent probe in biochemical studies, including in vitro models of neurodegeneration.

Research Area

Metabolism Research, Molecular Biology, Neuroscience

Key Properties

• CAS Number: 244-63-3
• MW: 168.19
• Purity: 95.16% (May vary between batches)
• Formula: C₁₁H₈N₂
• SMILES: CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1
• Target: Monoamine Oxidase,Endogenous Metabolite,DNA
• Solubility: DMSO:25 mg/mL (148.64 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (5.95 mM)

Bioactivity

• Target IC50:
  MAO-B:4.7 μM|MAO-A:3.34 μM (Ki)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Parkinson, Neuroprotection, oxidase, inhibit, Norharman, Norharmane, EndogenousMetabolite, Inhibitor, Monoamine, Monoamine Oxidase, MonoamineOxidase, MAO, 2,9-Diazafluorene, 2-Azacarbazole, Alkaloid, b-Carboline, Endogenous Metabolite, DNA, disease, beta-Carboline, Coffee, β-Carboline

Compound Identifiers

PubChem CID

1329