Norgestimate

SKU: orb1299730

Description

Norgestimate is a synthetic progestin, commonly formulated with ethinyl estradiol in oral contraceptives. It is used in research to study hormonal pharmacology, receptor interactions, and the effects of progestins in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 35189-28-7
• MW: 369.5
• Purity: 99.87% (May vary between batches)
• Formula: C₂₃H₃₁NO₃
• SMILES: [H][C@@]12CC[C@@](OC(C)=O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CC\C(C=C3CC[C@@]21[H])=N/O
• Target: Progesterone Receptor
• Solubility: DMSO:45 mg/mL (121.79 mM)

Bioactivity

• In Vivo:
  Norgestimate(NGM) inhibits the formation of biofilms by various staphylococcal strains. NGM is an acetylated progestin that is used as an oral contraceptive.NGM is swiftly converted in the liver and intestines to 17DN, a deacetylated metabolite with progestogenic properties.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

progestin, ProgesteroneReceptor, Progesterone Receptor, progesterone, deacetylated, levonorgestrel, norelgestromin, Norgestimate, NR3C3, inhibit, Inhibitor, metabolites, minimal, oral, 3-oxime, androgenicity, contraceptive

Compound Identifiers

PubChem CID

6540478