Norfluoxetine Hydrochloride

SKU: orb1306473

Description

Norfluoxetine Hydrochloride is the primary active metabolite of the antidepressant fluoxetine. It is widely used in pharmacological research to study serotonin reuptake inhibition in both in vitro binding assays and in vivo models of depression and related disorders.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 57226-68-3
• MW: 331.76
• Purity: 99.75%
• Formula: C₁₆H₁₇ClF₃NO
• SMILES: Cl.NCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1
• Target: Calcium Channel,Others,Drug Metabolite,5-HT Receptor
• Solubility: DMSO:60 mg/mL (180.85 mM);H2O:4 mg/mL (12.06 mM)

Bioactivity

• Target IC50:
  Cav 3.3:5 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CYP3A4, CYP2D6, CYP2C19, Drug Metabolite, CaV3.3, 5-hydroxytryptamine Receptor, 5-HT, 5-HT Receptor, Calcium Channel, Ca2+ channels, Ca channels, anticonvulsant, metabolite, N-demethylated, P450, inhibit, Norfluoxetine Hydrochloride, Norfluoxetine, Norfluoxetine HCl, Inhibitor, Fluoxetine, reuptake, serotonin, Serotonin Receptor

Compound Identifiers

PubChem CID

151371