NO-Losartan A

SKU: orb1694473

Description

Losartan is a potent AT1 receptor antagonist (Ki 5-20 nM) used to study hypertension and renal protection. Its NO-donor hybrid, NO-losartan A, combines AT1 blockade with nitric oxide-mediated vasodilation, making it a valuable tool for cardiovascular research in both in vitro and in vivo models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 791122-48-0
• MW: 602.04
• Formula: C₃₀H₂₈ClN₇O₅
• SMILES: C(N1C(COC(=O)C2=CC(CON(=O)=O)=CC=C2)=C(Cl)N=C1CCCC)C3=CC=C(C=C3)C4=C(C=CC=C4)C=5NN=NN5
• Target: Others,RAAS

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10371403