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nNOS-IN-2 trihydrochloride

SKU: orb3210518

Description

nNOS-IN-2 trihydrochloride is a nitric oxide synthase (nNOS) inhibitor capable of crossing the blood-brain barrier. It exhibits Ki values of 1.7 nM for human nNOS and 2.3 nM for rat nNOS, with high selectivity towards human eNOS and iNOS. Additionally, nNOS-IN-2 trihydrochloride effectively reduces PD-L1 expression in human melanoma cells under both basal conditions and IFN-γ exposure. This compound is suitable for researching melanoma and associated signaling pathways.

Images & Validation

Key Properties

TargetNO Synthase,IFNAR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information