NLRP3-IN-72

SKU: orb2944442

Description

NLRP3-IN-72 is a potent benzimidazole-based NLRP3 inflammasome inhibitor, demonstrating anti-inflammatory and antioxidant activity. It inhibits IL-1β release (IC50=0.3 µM), protects against pyroptosis (PD50=0.4 µM), and induces HO-1 (EC50=0.6 µM), making it a valuable tool for studying inflammatory diseases in cellular models.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 3043952-13-9
• MW: 353.393
• Formula: C₁₉H₂₀FN₅O
• SMILES: FC=1C=CC2=C(N=C(NC3=NC=4C=C(C=CC4O3)CN(C)CC)N2C)C1
• Target: NOD-like Receptor (NLR),Interleukin,Pyroptosis,ROS

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171810695