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NLRP3 IN 70

SKU: orb2893629

Description

Compound 15 (NLRP3 IN 70) is a potent and selective NLRP3 inflammasome inhibitor, demonstrating an IC50 of 23 nM for IL-1β suppression in THP-1 cells. This small molecule is a valuable research tool for investigating NLRP3-driven pathologies in both cellular and animal models of inflammatory and autoimmune diseases.

Research Area

Cell Biology

Images & Validation

Key Properties

MW406.54
FormulaC20H30N4O3S
SMILESO=C(NS(=O)(N(C)C1CCN(C)CC1)=O)NC2=C3C(CCC3)=CC4=C2CCC4

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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NLRP3 IN 70 (orb2893629)

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