NLRP3-IN-69

SKU: orb2944574

Description

NLRP3-IN-69 (Compound 23) is a small molecule inhibitor that blocks NLRP3 inflammasome assembly and NF-κBp65 activation. It reduces LPS-induced expression of IL-1β, iNOS, and COX-2, and inhibits nitric oxide production with an IC50 of 5.66 µM, demonstrating utility for in vitro anti-inflammatory research.

Research Area

Cell Biology

Key Properties

• CAS Number: 3027608-60-9
• MW: 436.454
• Formula: C₂₅H₂₄O₇
• SMILES: O(C(/C=C/C1=CC(OC)=C(OC)C(OC)=C1)=O)C2=CC3=C(C=C([C@@H](C(O)=O)C)C=C3)C=C2
• Target: Interleukin,COX,NO Synthase,NOD-like Receptor (NLR),NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176455418