NLRP3-IN-58

SKU: orb2695582

Description

NLRP3-IN-58 (DS15) is a small molecule inhibitor of the NLRP3 inflammasome, exhibiting an IC50 of 3.85 μM. At 10 μM, it suppresses IL-1β release by 33%. This compound is a useful research tool for studying NLRP3-driven inflammation in cellular models and related disease mechanisms.

Research Area

Cell Biology

Key Properties

• CAS Number: 2956014-05-2
• MW: 439.92
• Formula: C₂₂H₁₈ClN₃O₃S
• SMILES: O=C(NC1=CC=CC(=C1)S(=O)(=O)NC=2C=CC=CC2)CC3=CNC=4C=C(Cl)C=CC43
• Target: Interleukin,NOD-like Receptor (NLR)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172432002