Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

NLRP3-IN-45

SKU: orb2665407

Description

NLRP3-IN-45 (D6) is a potent and selective NLRP3 inflammasome inhibitor, with an IC50 of 41.79 nM against IL-1β. It blocks inflammasome assembly without affecting priming and has demonstrated efficacy in an LPS-induced acute lung injury (ALI) mouse model, supporting its use in researching NLRP3-driven inflammatory diseases.

Research Area

Cell Biology

Images & Validation

Key Properties

MW483.53
FormulaC27H30FNO6
TargetNOD-like Receptor (NLR)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

NLRP3-IN-45 (orb2665407)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%