NLRP3-IN-28

SKU: orb2565665

Description

NLRP3-IN-28 (N77) is a potent and selective NLRP3 inflammasome inhibitor, demonstrating an EC50 of 0.07 µM against nigericin-induced pyroptosis in vitro. It is a valuable research tool for studying NLRP3-driven pathologies, including inflammatory diseases, in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 2922814-80-8
• MW: 318.27
• Formula: C₁₂H₉F₃N₂O₃S
• SMILES: OC1=C(C2=CC=C(S(C)(=O)=O)N=N2)C=CC(C(F)(F)F)=C1
• Target: NOD-like Receptor (NLR),Pyroptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168157524