NLRP3-IN-21

SKU: orb1944421

Description

NLRP3-IN-21 (L38) is a small molecule inhibitor that blocks NLRP3 inflammasome activation and pyroptosis by targeting ASC oligomerization, inflammasome assembly, and gasdermin D cleavage. It has demonstrated anti-inflammatory effects in cellular models and is a useful research tool for studying NLRP3-driven pathologies like gout, atherosclerosis, and Alzheimer's disease.

Research Area

Cell Biology

Key Properties

• CAS Number: 2956791-61-8
• MW: 529.32
• Formula: C₂₀H₁₃Cl₂F₃N₆O₂S
• SMILES: C(C)(C)C=1N2C(=CC3=C2C=C(Cl)S3)C(=O)N(CC=4OC(=NN4)C5=C(Cl)N=C(C(F)(F)F)C=C5)N1
• Target: NOD-like Receptor (NLR)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

169450674