[Nle20] H4 peptide (16−23)

SKU: orb2664115

Description

The [Nle20] H4 peptide (16–23) is a potent and selective SETD8 inhibitor (Kd = 0.14 µM) that acts by competing for the histone substrate binding site. This tool compound is used in epigenetic research to study histone methylation's role in cancer cell proliferation and as a lead for anticancer therapeutic development.

Key Properties

• CAS Number: 2042178-19-6
• MW: 1077.33
• Formula: C₄₇H₈₈N₂₀O₉
• SMILES: [C@H](CC1=CN=CN1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CC(C)C)=O)C(C)C)=O)CCCC)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@H](CCCCN)N)=O)CCCNC(=N)N)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172419332