Nitroaspirin

SKU: orb1307961

Description

Nitroaspirin (NCX 4016) is a nitric oxide-donating aspirin derivative that acts as an irreversible COX-1 inhibitor with antiplatelet effects. It demonstrates research utility in oncology, inducing apoptosis and cell cycle arrest in resistant ovarian cancer cells in vitro by suppressing EGFR/PI3K/STAT3 pathways and modulating Bcl-2 proteins.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience

Key Properties

• CAS Number: 175033-36-0
• MW: 331.28
• Purity: 99.32% (May vary between batches)
• Formula: C₁₆H₁₃NO₇
• SMILES: O(C(C)=O)C1=C(C(OC2=CC(CON(=O)=O)=CC=C2)=O)C=CC=C1
• Target: Apoptosis,COX
• Solubility: DMSO:55 mg/mL (166.02 mM);10% DMSO+90% Corn Oil:5 mg/mL (15.09 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, NCX4016, NCX-4016, NCX 4016, Nitroaspirin, inhibit, COX, COX-1, Cyclooxygenase, Apoptosis

Compound Identifiers

PubChem CID

119032