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NITD-2

SKU: orb1219042

Description

NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in humans. Neither vaccine nor antiviral therapy is currently available for DENV.

Images & Validation

Key Properties

CAS Number1197896-79-9
MW433.48
Purity>98% (HPLC)
FormulaC23H19N3O4S
SMILESO=C(O)C1=CC=CC=C1NS(=O)(C2=CC=CC(C3=CN(CC4=CC=CC=C4)N=C3)=C2)=O
TargetDNA/RNA Synthesis
SolubilityDMSO:10 mM

Bioactivity

In Vitro
NITD-2 inhibits de novo RNA synthesis. NITD-2 exhibited no antiviral activity in cell culture resulted from the poor cell penetratration.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

NITD-2 (orb1219042)

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Available Sizes

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200 mg
500 mg
5 mg
$ 320.00
10 mg
$ 480.00
25 mg
$ 780.00
50 mg
$ 1,110.00
100 mg
$ 1,510.00