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Nisoxetine hydrochloride

SKU: orb1217860

Description

Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor.

Images & Validation

Key Properties

CAS Number57754-86-6
MW307.82
Purity>98% (HPLC)
FormulaC17H21NO2·HCl
SMILESCNCCC(C1=CC=CC=C1)OC2=CC=CC=C2OC.Cl
TargetMonoamine Transporter
SolubilityH2O:<30.78mg/ml

Bioactivity

In Vivo
Animal model: Sprague-Dawley rats(290-340 g). Dosage: 0.6, 1.2, 1.8, 2.2 μM. Administration: A single intrathecal injection. Result: Showed ED50s of 0.82, 0.75 and 0.70 μM in blocking motor function, proprioception, and nociception respectively.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

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