Niraparib metabolite M1 HCl

SKU: orb2815838

Description

Niraparib metabolite M1 HCl is the active metabolite of Niraparib, as a novel targeted ADP ribose polymerase (PARP) inhibitor, it can competitively inhibit PARP1 and PARP2 to block the DNA repair mechanism of tumor cells and thus effectively inhibit the growth and proliferation, which is commonly used in the study of ovarian cancer, fallopian tube cancer and primary peritoneal cancer, and is commonly used in the study of ovarian, fallopian tube and primary peritoneal cancers.

Key Properties

• MW: 357.83
• Purity: 97.61%
• Formula: C₁₉H₂₀ClN₃O₂
• SMILES: OC(C1=CC=CC2=CN(C3=CC=C([C@@H]4CCCNC4)C=C3)N=C12)=O.Cl
• Target: PARP

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PARP