Niraparib metabolite M1 HCl

SKU: orb2815838

Description

Niraparib metabolite M1 HCl is the active metabolite of the PARP inhibitor niraparib, competitively inhibiting PARP1 and PARP2 to disrupt DNA repair in cancer cells. It is widely used in preclinical in vitro and in vivo studies for ovarian, fallopian tube, and primary peritoneal cancers.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• Target: PARP
• Molecular Weight: 357.83
• Purity: 97.61%
• Formula: C₁₉H₂₀ClN₃O₂
• SMILES: OC(C1=CC=CC2=CN(C3=CC=C([C@@H]4CCCNC4)C=C3)N=C12)=O.Cl

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

M1 metabolite of niraparib HCl, Niraparib carboxylic acid metabolite M1 HCl, Niraparib metabolite M1 HCl (1476777-06-6 Free base)

Compound Identifiers

PubChem CID

175663003