Nidufexor

SKU: orb1299414

Description

Nidufexor is a potent and selective small molecule agonist of the farnesoid X receptor (FXR). It is a valuable research tool for studying FXR's role in metabolic disorders, including liver diseases, and has been utilized in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 1773489-72-7
• MW: 487.93
• Purity: 99.79% (May vary between batches)
• Formula: C₂₇H₂₂ClN₃O₄
• SMILES: Cn1nc(C(=O)N(Cc2ccccc2)Cc2ccc(cc2)C(O)=O)c2COc3ccc(Cl)cc3-c12
• Target: Autophagy,FXR
• Solubility: DMSO:80 mg/mL (163.96 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.76 mM);H2O:Insoluble

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

LMB 763, LMB763, LMB-763, NR1H4, Inhibitor, inhibit, Nidufexor, FXR, Autophagy

Compound Identifiers

PubChem CID

118063735