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Nicotinamide Hydrochloride

SKU: orb1745074

Description

Nicotinamide Hydrochloride is a vitamin B3 form that acts as a SIRT2 inhibitor (EC₅₀ ~2 µM), reducing melanoma cell proliferation in vitro and elevating NAD⁺, ATP, and ROS. It demonstrates in vivo efficacy by suppressing tumor growth and extending survival in melanoma models, supporting research into skin cancer therapeutics.

Research Area

Epigenetics & Chromatin, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number25334-23-0
MW158.59
FormulaC6H7ClN2O
SMILESCl.O=C(N)C=1C=NC=CC1
TargetEndogenous Metabolite,HBV,Sirtuin,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information