Niclosamide sodium

SKU: orb1744854

Description

Niclosamide sodium (BAY2353) is an orally bioavailable antihelminthic agent repurposed as a potent STAT3 inhibitor, with an IC50 of 0.25 μM in HeLa cells. Its research applications extend to oncology and virology, where it has been shown to inhibit cancer cell proliferation and disrupt DNA replication in Vero E6 cells in vitro.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 40321-86-6
• MW: 349.1
• Formula: C₁₃H₇Cl₂N₂NaO₄
• SMILES: O=[N+]([O-])C1=CC(Cl)=C(NC(C2=C([O-])C=CC(Cl)=C2)=O)C=C1.[Na+]
• Target: Others,Antibiotic,Parasite,STAT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25217869