NHWD-870

SKU: orb1693615

Description

NHWD-870 is a potent and selective BET bromodomain inhibitor targeting BRD2, BRD3, BRD4, and BRDT. It demonstrates robust anti-tumor activity in vitro and in vivo by inducing apoptosis and inhibiting proliferation, and it disrupts tumor cell-macrophage interactions within the tumor microenvironment.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 2115742-03-3
• MW: 491.59
• Formula: C₂₉H₂₉N₇O
• SMILES: Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc3n(C)ncc3cc21
• Target: Epigenetic Reader Domain,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137448679