NH2-UAMC1110 TFA

SKU: orb2278814

Description

NH2-UAMC1110 TFA is a modified derivative of the potent and selective fibroblast activation protein (FAP) inhibitor UAMC1110, featuring an aminobutoxy linker for conjugation in the synthesis of FAPI-QS tracers. It exhibits low nanomolar inhibition of FAP and related dipeptidyl peptidases (DPP4, DPP9, DPPII, and PREP), making it a valuable tool for in vitro and in vivo cancer research, particularly in the development of targeted imaging and therapeutic agents.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2990021-73-1
• MW: 545.46
• Purity: 99.85% (May vary between batches)
• Formula: C₂₃H₂₄F₅N₅O₅
• SMILES: C(C(O)=O)(F)(F)F.C(NCC(=O)N1[C@H](C#N)CC(F)(F)C1)(=O)C=2C3=C(C=CC(OCCCCN)=C3)N=CC2
• Target: Others,Immunology/Inflammation related
• Solubility: H2O:200 mg/mL (366.66 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

FAP

Compound Identifiers

PubChem CID

163197094