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Catalog Number | orb2278814 |
---|---|
Category | Small Molecules |
Description | NH2-UAMC1110 TFA is a derivative of UAMC1110 bearing an aminobutoxy group for the synthesis of FAPI-QS. UAMC1110 is a novel selective fibroblast-activated protein (fap) inhibitor exhibiting low nanomolar inhibition of the related dipeptidyl peptidases (dpps), dppiv, dpp9, dppii, and (prep). dppiv, dpp9, dppii, and (prep). |
Purity | 99.02% |
MW | 545.46 |
Biological Activity | NH2-UAMC1110 TFA, a derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110, serves as a precursor in the formation of FAPI-QS, a chelating agent crucial for creating radiotracers with high tumor selectivity and potency for tumor diagnosis and therapy [1] [2]. |
CAS Number | 2990021-73-1 |
Formula | C23H24F5N5O5 |
SMILES | C(C(O)=O)(F)(F)F.C(NCC(=O)N1[C@H](C#N)CC(F)(F)C1)(=O)C=2C3=C(C=CC(OCCCCN)=C3)N=CC2 |
Storage | -20°C |
Note | For research use only |