NF-κB/MAPK-IN-1

SKU: orb1686922

Description

NF-κB/MAPK-IN-1 is a dual-pathway inhibitor that suppresses NF-κB and MAPK signaling, demonstrating anti-inflammatory effects by reducing NO, iNOS, and COX-2 expression. It is utilized in rheumatoid arthritis research, with studies showing its activity in both cellular assays and animal models of inflammation.

Research Area

Immunology & Inflammation, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 2413940-56-2
• MW: 477.51
• Purity: 97.30% (May vary between batches)
• Formula: C₂₇H₂₇NO₇
• SMILES: O(C1=C(C(C)=O)C=CC(OC)=C1)C2=CC=C(NC(/C=C/C3=CC(OC)=C(OC)C(OC)=C3)=O)C=C2
• Target: p38 MAPK,NF-κB,NO Synthase,MAPK,COX
• Solubility: DMSO:80 mg/mL (167.54 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MAPK, NF-κB, NFκB, NF-kB, NFkB

Compound Identifiers

PubChem CID

148976305