NF-κB-IN-19

SKU: orb2944539

Description

NF-κB-IN-19 is a small molecule inhibitor that targets the NF-κB pathway, inducing DNA damage, ROS production, autophagy, and apoptosis in tumor cells. It demonstrates antiproliferative effects by modulating PI3K/AKT/STAT-3 signaling and inhibiting VEGF/HIF-1α, showing potential in vitro for overcoming cisplatin resistance in cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• MW: 759.92
• Formula: C₂₄H₂₆Cl₃F₂N₃O₄Pt
• Target: STAT,PI3K,HIF/HIF Prolyl-Hydroxylase,Akt,ROS,Apoptosis,Reactive Oxygen Species,NF-κB,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

STAT,PI3K,HIF/HIF Prolyl-Hydroxylase,Akt,ROS,Apoptosis,Reactive Oxygen Species,NF-κB,Autophagy