NF-κB-IN-18

SKU: orb2945869

Description

NF-κB-IN-18 (Compound 5k) is an orally bioavailable inhibitor that targets the NF-κB pathway by suppressing p65 phosphorylation. It exhibits potent anti-inflammatory effects in vivo, as demonstrated in a murine model of xylene-induced ear edema, supporting its use in inflammation-related research.

Research Area

Signal Transduction

Key Properties

• CAS Number: 3121879-82-8
• MW: 500.542
• Formula: C₂₉H₂₈N₂O₆
• SMILES: CC1(C=CC2=C3C(=C(C(=C2O1)C(=O)OC)OCC(=O)NC4=CC5=C(C=C4)N=CC=C5)C=CC(O3)(C)C)C
• Target: NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677067