Nerofe

SKU: orb2813737

Description

Nerofe is the endogenous ligand for the ST2 receptor (IL1RL1), a key modulator of type 2 immunity. This small molecule is a critical tool for investigating ST2-mediated signaling in both cellular assays and in vivo models of allergic and fibrotic diseases.

Research Area

Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction

Key Properties

• Target: JNK,Interleukin,p38 MAPK,IFNAR,Apoptosis,Caspase
• CAS Number: 2120397-85-3
• MW: 1897.18
• Formula: C₉₆H₁₂₉N₂₁O₂₀
• SMILES: C([C@H](C(N[C@@H](C(N[C@@H](C(N[C@H](CCCCN)C(O)=O)=O)CCCNC(=N)N)=O)CCC(O)=O)=O)NC([C@H](NC([C@H](NC([C@H](NC(=O)[C@@H]1N(C([C@H](NC([C@@H](CC2=CC=CC=C2)NC([C@@H](CC3=CC=CC=C3)NC([C@H](NC([C@@H](CC=4C=5C(NC4)=CC=CC5)NC([C@@H](CC=6C=7C(NC6)=CC=CC7)N)=O)=O)[C@H](C)O)=O)=O)=O)CC(C)C)=O)CCC1)CO)=O)[C@H](C)O)=O)CC(C)C)=O)C=8C=9C(NC8)=CC=CC9

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

145722610