Neoechinulin A

SKU: orb1682035

Description

Neoechinulin A exhibits anti-inflammatory activity in LPS-stimulated RAW264.7 macrophages by suppressing the NF-κB and p38 MAPK pathways. It shows potential for neuroinflammation research in Alzheimer's disease models and has demonstrated cytoprotective effects against rotenone-induced toxicity in vitro through antioxidant mechanisms.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 51551-29-2
• MW: 323.39
• Formula: C₁₉H₂₁N₃O₂
• SMILES: C[C@@H]1NC(=O)\C(NC1=O)=C\c1c([nH]c2ccccc12)C(C)(C)C=C
• Target: IκB/IKK,ASK,NOS,TNF,p38 MAPK,COX,NF-κB,Apoptosis,Beta Amyloid,Prostaglandin Receptor,NADPH-oxidase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9996305