Neochlorogenic acid

SKU: orb1221665

Description

Chlorogenic acid has resistance to the brown rot fungus, may by interfering with fungal melanin production.

Key Properties

• CAS Number: 906-33-2
• MW: 354.31
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₈O₉
• SMILES: C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O
• Target: Src
• Solubility: DMSO : 11 mg/mL 31.05 mM

Bioactivity

• In Vitro:
  Neochlorogenic acid (NCA) shows a reduction of lipopolysaccharide (LPS)-induced NO production by suppressing iNOS and COX-2 protein expression and production of pro-inflammatory cytokines, such as TNF-α and IL-1β, in BV2 microglia cells. In addition, phosphorylated p38 MAPK and NF-κB p65 are also inhibited by Neochlorogenic acid in activated microglia. iNOS and COX-2 levels are increased in LPS-induced BV2 cells, but this increase is significantly inhibited after treatment with 50 and 100 μM Neochlorogenic acid.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

trans-5-O-Caffeoylquinic acid

Quick Database Links

Gene Symbol

Src