Nemorubicin

SKU: orb1302833

Description

Nemorubicin (PNU 152243) is a doxorubicin analog with a distinct antitumor spectrum, metabolic pathway, and toxicity. It demonstrates activity against tumors resistant to various chemotherapeutics, including alkylating agents and platinum drugs. Research applications include investigating its novel mechanism in both in vitro and in vivo models of multidrug-resistant cancers.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 108852-90-0
• MW: 643.64
• Purity: 97.79% (May vary between batches)
• Formula: C₃₂H₃₇NO₁₃
• SMILES: [H][C@@]1(C[C@@](O)(Cc2c(O)c3C(=O)c4cccc(OC)c4C(=O)c3c(O)c12)C(=O)CO)O[C@H]1C[C@@H]([C@H](O)[C@H](C)O1)N1CCO[C@@H](C1)OC
• Target: Others,DNA/RNA Synthesis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (3.88 mM);DMSO:45 mg/mL (69.91 mM)

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PNU-152243A, PNU152243, PNU-152243, PNU 152243, Methoxymorpholinyl doxorubicin, Methoxymorpholinyldoxorubicin, Nemorubicin, inhibit, Inhibitor, FCE23762, FCE-23762, FCE 23762

Compound Identifiers

PubChem CID

65907