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Necroptosis inducer 1

SKU: orb3210036

Description

Necroptosis inducer1 is an agent that induces necroptosis, a type of cell death. It inhibits the activity of thioredoxin reductase (TrxR), elevates intracellular ROS levels, triggers ROS-mediated necroptosis, and promotes immunogenic cell death dependent on necroptosis. Necroptosis inducer1 can suppress tumor growth, remodel the tumor immune microenvironment, and shows synergy with anti-PD-1 treatments in animal models. It is applicable in colon cancer research.

Images & Validation

Key Properties

TargetROS,Necroptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information