Necrocide 1

SKU: orb2278909

Description

Necrocide 1 is a small molecule that potently induces cancer cell necrosis via the mitochondrial pathway. Its nanomolar activity is unaffected by caspase inhibition, BCL2 overexpression, or TNFα neutralization. This compound is a valuable research tool for studying non-apoptotic cell death mechanisms in both in vitro and in vivo cancer models.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1247028-61-0
• MW: 365.47
• Formula: C₂₃H₂₇NO₃
• SMILES: O=C1[C@](C=2C(N1)=C(C)C(OC)=CC2)(C3=CC=C(O)C=C3)C4CCCCCC4
• Target: PERK,Necroptosis,Others,ROS,TRP/TRPV Channel

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46919880