NCATS-SM4420

SKU: orb2664920

Description

NCATS-SM4420 (Compound A35) is an orally active TSHR ligand that inhibits proliferation of thyroid cancer cell lines MDA-T32 and MDA-T85 (IC50 0.71 μM and 0.38 μM) and suppresses metastasis in mouse models, showing potential for thyroid cancer research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1352286-61-3
• MW: 521.56
• Formula: C₃₁H₂₇N₃O₅
• SMILES: O=C(NC1=CC=C(OCC=2C=C(C=CC2OC)C3=NC=4C=CC=C(O)C4C(=O)N3CC=5C=CC=CC5)C=C1)C
• Target: TSH Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

49789113