NC-002

SKU: orb3180308

Description

NC-002 is a cell-penetrating peptide and functions as an inhibitor of the trypsin-like proteasome (Trypsin-likeproteasome), without affecting the activity of lysosomal cysteine proteases. It is an epoxyketone derivative of Leupeptin. NC-002 enhances the sensitivity of myeloma cells to Bortezomib and Carfilzomib and is utilized in cancer research.

Key Properties

• Target: Proteasome
• CAS Number: 1356828-46-0
• MW: 482.63
• Formula: C₂₃H₄₂N₆O₅
• SMILES: C([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)CC(C)C)=O)CCCNC(=N)N)(=O)[C@@]1(C)CO1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Proteasome