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NBI-27914

SKU: orb3027225

Description

NBI-27914 is a selective, non-peptide antagonist of the corticotropin-releasing factor receptor 1 (CRFR1). It demonstrates analgesic properties and inhibits CRF-induced anxiety behaviors, making it a valuable research tool for studying stress-related disorders in both in vitro and in vivo models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number184241-44-9
MW434.19
Purity99.64%
FormulaC18H20Cl4N4
SMILESClC=1C=C(Cl)C(NC=2N=C(N=C(C2Cl)N(CCC)CC3CC3)C)=C(Cl)C1
TargetCRFR
SolubilityDMSO:80 mg/mL (184.25 mM)

Storage & Handling

Storagekeep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NBI27914

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Protocol Information

NBI-27914 (orb3027225)

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Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 130.00
1 ml x 10 mM (in DMSO)
$ 140.00
10 mg
$ 190.00
25 mg
$ 360.00