NBD-2

SKU: orb3142374

Description

NBD-2 is an inhibitor targeting the NEMO-IKKα/β interaction within the NF-κB signaling pathway. It can specifically suppress the canonical NF-κB signaling both in vitro and in vivo, thereby reducing the inflammatory response in acute lung injury (ALI) induced by lipopolysaccharide (LPS). NBD-2 demonstrates significant anti-inflammatory activity and is applicable for research on diseases related to the NF-κB signaling pathway, such as autoimmune disorders and cancer.

Research Area

Signal Transduction

Key Properties

• Target: NF-κB
• Formula: C₇₃H₈₆F₈N₁₄O₁₇S₂

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NF-κB