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Naratriptan hydrochloride

Naratriptan hydrochloride

Catalog Number: orb1300624

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$ 150.00
Catalog Numberorb1300624
CategorySmall Molecules
DescriptionNaratriptan hydrochloride
Purity99.89%
MW371.93
Biological ActivityNaratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydrochloride) binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides.
CAS Number[143388-64-1]
FormulaC17H25N3O2S·HCl
SMILESCl.CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1
Storage-20°C
NoteFor research use only
  • Naratriptan hydrochloride [orb1222699]

    > 98% (HPLC)

    143388-64-1

    371.9

    C17H25N3O2S·HCl

    1 g, 500 mg, 200 mg, 50 mg, 10 mg, 25 mg, 100 mg
  • Naratriptan D3 Hydrochloride [orb1992761]

    98.00%

    1190021-64-7

    374.94

    C17H26ClN3O2S

    500 mg, 100 mg