Naratriptan hydrochloride

SKU: orb1300624

Description

Naratriptan Hydrochloride is a selective serotonin 5-HT1B/1D receptor agonist used as an anti-migraine agent. Its mechanism involves cranial vasoconstriction and inhibition of pro-inflammatory neuropeptide release from trigeminal nerves, which has been validated in both in vitro receptor binding assays and in vivo models of migraine.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 143388-64-1
• MW: 371.93
• Purity: 99.93% (May vary between batches)
• Formula: C₁₇H₂₅N₃O₂S·HCl
• SMILES: Cl.CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1
• Target: 5-HT Receptor
• Solubility: DMSO:65 mg/mL (174.76 mM);H2O:20 mg/mL (53.77 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Serotonin Receptor, 5-HT Receptor, 5-HT1, Amerge, 5HTReceptor, 5-hydroxytryptamine Receptor, 5HT Receptor, Inhibitor, GR-85548A, GR-85548A Hydrochloride, GR-85548A hydrochloride, inhibit, Naramig, Naratriptan, Naratriptan HCl, Naratriptan Hydrochloride, Naratriptan hydrochloride

Compound Identifiers

PubChem CID

60875