Naquotinib mesylate

SKU: orb1741537

Description

Naquotinib mesylate (ASP8273) is an orally bioavailable, irreversible EGFR inhibitor that selectively targets mutant forms (iC50 8-33 nM) over wild-type (iC50 230 nM). It is a research compound used in preclinical studies for non-small cell lung cancer, demonstrating activity in both cellular assays and in vivo models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1448237-05-5
• MW: 658.81
• Formula: C₃₁H₄₆N₈O₆S
• SMILES: CS(O)(=O)=O.CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCC(CC2)N2CCN(C)CC2)nc1O[C@@H]1CCN(C1)C(=O)C=C
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

92135932